Day: October 9, 2021

This comprises inhibition of HR, a shift to more error prone repair and loss of checkpoint function leading to fragmentation of chromosomal material

This comprises inhibition of HR, a shift to more error prone repair and loss of checkpoint function leading to fragmentation of chromosomal material. assessed in vivo. Results The combination of AUY922 with cisplatin, radiation and CCRT was found to be synergistic in p53 mutant HNSCC. AUY922 prospects to significant alterations to the DDR induced by […]

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