Day: November 16, 2021

In this study, we show that HDAC inhibitors induce delayed cardiotoxicity in hiPS-CMs at clinically relevant concentrations

In this study, we show that HDAC inhibitors induce delayed cardiotoxicity in hiPS-CMs at clinically relevant concentrations. sustained contractions and fibrillation-like patterns. Transcriptional changes that are common between the cardiotoxic HDAC inhibitors but different from noncardiotoxic treatments recognized cardiac-specific genes and pathways related to structural and practical changes in cardiomyocytes. Combining the practical data with […]

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