Identified using recombinant NL4.3 computer virus (T124A IN mutant). Table 4 Orotic acid (6-Carboxyuracil) In Vitro ADME Profile of Compound 26 Open in a separate window EC50 range,a nM11C27serum shift (50% HS), fold-changeb2.1HLM/RLM ( em t /em 1/2),?min210/ 300Caco-2 ( em P /em app), ?106?cm/s14CyP450 inh. mg/mL 0.85 Open in a separate window aDetermined with […]