Purified PenA1 and AmpC1 were used as controls. Temocillin is a potent inactivator of AmpC1 but not PenA1. In addition, temocillin demonstrated efficacy in infection models as well as in patients (19,C21). Temocillin was previously shown to possess antimicrobial activity against members of the complex (Bcc), a group of Gram-negative pathogens that cause infections in […]