These chimeric mice contained NP-specific IgG-BCR-expressing B cells which have under no circumstances encountered the cognate antigen (termed IgG-BCR-ESC B cells)60. much less high-affinity Ab muscles in secondary reactions. These findings claim that SAP97-deficiency will not stop B cells from proceeding through GC reactions, and rather SAP97-lacking B cells most likely would neglect to contend […]