The isolates were grown in Todd-Hewitt broth (Oxoid, Adelaide) supplemented with 1% (wt/vol) neopeptone (Difco). protease, SpyCEP, which safeguarded IL-8 and enhanced neutrophil ingress to the site of illness. We have now substituted the carrier protein, diphtheria toxoid with its superior analogue, CRM197 which provides better immunogenicity and is widely used in licenced human being […]