?(Fig.33mutant mast cells. of potential goals of pharmaceutical interference for the treating other and allergic immunologic diseases. Btk (Bruton’s tyrosine kinase) and Syk are protein-tyrosine kinases that play essential jobs in B cell and mast cell activation (1C3). Mutations in the gene result in X-linked agammaglobulinemia in human beings (4, 5) and X-linked immunodeficiency (mutations […]