The New England Journal of Medicine. that up-regulated IL-6 plays an important role in the development of EGFR-TKI-induced interstitial fibroblastic proliferation. Therefore, blocking of IL-6 signaling could be beneficial to malignancy patients undergoing EGFR-TKI treatment for reducing the risk of its unfavorable effects. and amplification, and the conversation between EGFR and HER-2 and so on […]