The elimination half-lives range from 1.6?days (Nb100) to 7.6?days (Nb75), which correspond to approximately (S)-(-)-5-Fluorowillardiine 771-fold improvement compared to the control Nb (Figures 4B and 4C; Data S2). (NbHSA) that can be readily fused to small biologics for half-life extension. We characterized the thermostability, binding kinetics, and cross-species reactivity of NbHSAs, mapped their epitopes, and […]