4A). All treatment arms significantly inhibited xenograft growth, particularly lapatinib/trastuzumab, LJM716/trastuzumab and the 3-drug combination. Mice treated with any of these three combinations exhibited a close to total response with tumors measuring 25% growth inhibition (GI) relative to control, in 6/18 (33%) cell lines as measured by the cell content of ATP (CellTiterGlo assay). Treatment […]
Successful cloning of the ORFs into pFBq was verified through Sanger sequencing at the Central Analytical DNA Sequencing Facility (Stellenbosch University, South Africa)
Successful cloning of the ORFs into pFBq was verified through Sanger sequencing at the Central Analytical DNA Sequencing Facility (Stellenbosch University, South Africa). Open in a separate window Figure 1 Schematic presentation of the baculovirus expression strategies used to generate RV-VLPs.The donor plasmids contains ORFs coding for specific rotavirus proteins (labelled downstream to the promoters […]
We’ve demonstrated that pT231-tau isn’t just a monomeric p-tau epitope but may be the drivers of tau aggregation
We’ve demonstrated that pT231-tau isn’t just a monomeric p-tau epitope but may be the drivers of tau aggregation. However the stage can be CPI-637 which phosphorylated tau may be the most critical type to be taken off the brain, because removal of physiologic tau could cause neurodegenerative outcome especially. Recently, we’ve demonstrated that phosphorylated tau […]
The study was approved by the Tel Aviv University Institutional animal care and use committee and performed in compliance with their guidelines
The study was approved by the Tel Aviv University Institutional animal care and use committee and performed in compliance with their guidelines. Proteins and antibodies Mouse PCPE-1 (mPCPE-1) was purified from culture media of 3T6 mouse fibroblasts by ammonium sulfate fractionation, gel-filtration, lysyl-Sepharose chromatography and affinity chromatography on Sepharose coupled to the C-propeptide of type […]
The ROC analyzes the ability of IGRA to discriminate INF response in vaccinated HCWs (T2) versus baseline INF response (T0) to the Spike antigen of SARS-CoV-2
The ROC analyzes the ability of IGRA to discriminate INF response in vaccinated HCWs (T2) versus baseline INF response (T0) to the Spike antigen of SARS-CoV-2.The Youden index (i.e., cutoff at the highest sum of specificity and sensitivity) is 72 mIU/mL. found between INF and anti-RBD Abs values (test. Correlation between continuous variables was performed […]