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Quantitative RT-PCR analysis revealed increased expression of these p53 genes in the transcription level (Fig

Quantitative RT-PCR analysis revealed increased expression of these p53 genes in the transcription level (Fig. mediates the association between MDMX and MDM2 (6, 7). Genetic studies have shown that like MDM2, MDMX is definitely another essential bad regulator of p53 (8C10). Although it remains unclear why both MDM2 and MDMX are required for p53 control, […]

In the control animals (n?=?8, perfusion with isotonic saline only), the bicarbonate secretion was steady during the test

In the control animals (n?=?8, perfusion with isotonic saline only), the bicarbonate secretion was steady during the test. inside a concentration-dependent Rabbit Polyclonal to PTTG way, as the net liquid flux didn’t change. Pre-treatment using the CFTR inhibitor CFTRinh172 (i.p. or i.v.) didn’t modification the secretory response to ethanol, even though removing Cl? through the […]

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