8 D), indicating that the findings for the IAP antagonist depicted inFigs. of cellular FLICE-inhibitory protein (cFLIP). However, only cFLIPLand not cFLIPSinterfered with RIP1 recruitment to the DISC and complex II and protected cells from death. These results demonstrate a fundamental role for RIP1 in CD95 signaling and provide support for a physiological role of […]