The main clues concerning the function of PRICKLE1 come from studies showing it is a member of the noncanonical WNT pathway, regulates planar cell polarity (PCP) and intracellular calcium release, and is characterized by PET and LIM domains[8],[9]. rules of neurotransmitter launch. Endogenous Prickle1 and Syn1 co-localize in neurons and actually interact via theSYN1region mutated […]